The food processing and packaging industry has been using antimicrobial active packaging as a tool for maintaining the quality of perishable products and they can also increase the shelf life. This change has been brought since the use of synthetic materials cause environmental impacts due to inappropriate disposal. Therefore, eco-friendly polymer materials from renewable sources are used as alternatives to reduce such problems. This idea has set out to develop biodegradable antimicrobial films comprising poly butylene adipate-co-terephthalate (PBAT) and oregano essential oil (OEO).Films can be produced by hot-melt extrusion. The morphological, mechanical, physical, water barrier, and structural properties are to be characterized. Their bioactive, antioxidant, and antimicrobial activities should also be analyzed.Oregano essential oil bioactive compounds are found in the extruded films. The incorporation of Oregano essential oil may or may not affect the thermal properties,the mechanical attributes of the films. Through microbiological assays the effectiveness of the films in lessening total coliforms and microorganisms can be evaluated. If the Oregano essential oil concentration is higher, the antioxidant activity will also be higher. The films produced by this idea can be used as an active packaging system to control microbial growth in perishable products. Additionally, their mechanical, thermal, and water barrier properties to be suitable for food packaging applications.